FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

FILE - This Thursday, March 18, 2021 file photo shows syringes filled with the Moderna COVID-19 vaccine at a pop up site in the Queens borough of New York. According to results released on Monday, March 29, 2021, The U.S government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies. (AP Photo/Mary Altaffer)

COVID vaccine found highly effective in real-world U.S. study

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses,

The U.S. government’s first look at the real-world use of COVID-19 vaccines found their effectiveness was nearly as robust as it was in controlled studies.

The two vaccines available since December — Pfizer and Moderna — were highly effective at 90% after two doses, the Centers for Disease Control and Prevention reported Monday. In testing, the vaccines were about 95% effective in preventing COVID-19.

“This is very reassuring news,” said the CDC’s Mark Thompson, the study’s lead author. “We have a vaccine that’s working very well.”

The study is the government’s first assessment of how the shots have been working beyond the drugmakers’ initial experiments. Results can sometimes change when vaccines are used in larger, more diverse populations outside studies.

With nearly 4,000 participants from six states, the study focused on health care workers, first responders and other front-line workers who had first priority for the shots because they are at higher risk. They were given nasal swab test kits to use every week to check for signs of a coronavirus infection.

“The evidence base for (currently available) COVID-19 vaccines is already strong, and continues to mount ever higher with studies like this one,” said David Holtgrave, dean of the University at Albany’s School of Public Health, in an email.

The study included roughly 2,500 volunteers who had completed two vaccine doses, about 500 who got one dose and about 1,000 who did not get vaccinated between mid-December and mid-March.

The researchers counted 205 infections, with 161 of them in the unvaccinated group. Of the remaining 44, the CDC said 33 of them were in people apparently infected within two weeks of a shot. Experts say it takes two weeks before a dose takes full effect.

No one died, and only two were hospitalized. Thompson did not say whether the people hospitalized were vaccinated or not.

Besides the 90% figure for two doses, the study found it was 80% effective for participants two weeks or more after a first dose.

CDC Director Dr. Rochelle Walensky called the study’s findings “tremendously encouraging.”

“Our national vaccination efforts are working,” she said during a White House press briefing Monday. She added that over 93 million Americans have received at least one vaccine dose and over 51 million people have been fully vaccinated.

Different researchers have tried to look at how the vaccines have performed in real-life conditions, including work done in Israel and the United Kingdom, and a U.S. study of Mayo Clinic patients.

Unlike the Mayo study, which focused on hospitalization and death, the CDC study looked for any infection — including infections that never resulted in symptoms, or were detected before people started feeling sick.

About two-thirds of the vaccinations in the study were Pfizer shots, one-third were Moderna and five people got the newest single-dose shot from Johnson & Johnson. The study was done in Miami; Duluth, Minnesota; Portland, Oregon; Temple, Texas; Salt Lake City; and Phoenix and other areas in Arizona.

Moderna, meanwhile, announced Monday that it had shipped its 100 millionth dose to the U.S. government, meeting its pledge to supply that amount by the end of March. The company said it expects to meet its next deadlines, of delivering another 100 million doses by the end of May and its final 100 million by the end of July.

READ MORE: B.C.’s frontline worker vaccine program in flux as AstraZeneca use paused for under-55s

___

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.

Mike Stobbe, The Associated Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Saanich’s Malia Brodie competed in the Vancouver qualifiers for the 2020 National Championships. (Photo by BC Sport Karate Snaps)
PHOTOS: Saanich teen awarded $1,800 Karate Canada bursary to pursue officiant certification

Malia Brodie, 18, has black belt, nearly 15 years experience in karate

Saanich police officers were one group of dozens that submitted dance clips to the Greater Victoria Festival Society, to help create the Dance Across Victoria video montage. (Youtube/Screenshot)
WATCH: Saanich police, Victoria mayor bust some moves in new Dance Across Victoria video

Montage features submitted dance clips from across Greater Victoria

Former Oak Bay High Grade 12 student Brandon Kip plays the $100,000 Steinway piano in the Dave Dunnet Theatre. (Black Press Media file photo)
Oak Bay High Alumni Association passes torch to new president

The association has given back more than $70,000 in its 16 years

This photo courtesy of Leanne Grover shows the immediate aftermath of the fire at 7987 Galbraith Cres. that caused extensive damage and displaced six residents. (Leanne Grover/Submitted)
Residents of a Central Saanich duplex ‘fortunate’ to escape Sunday morning fire

Damage to the duplex extensive with one resident said to be ‘catatonic’ after escaping building

After more than a year, open forums will resume at a Saanich committee of the whole meeting on April 19 with up to five residents having the chance to speak for three minutes each about any district-related matter. (Black Press Media file photo)
Public input resumes at Saanich council following lengthy suspension due to pandemic

Up to five residents can present by phone for up to three minutes starting April 19

Vancouver resident Beryl Pye was witness to a “concerning,” spontaneous dance party that spread throughout social groups at Kitsilano Beach on April 16. (Screen grab/Beryl Pye)
VIDEO: Dance party erupts at Vancouver’s Kitsilano Beach to the dismay of onlookers

‘It was a complete disregard for current COVID-19 public health orders,’ says Vancouver resident Beryl Pye

Deputy Prime Minister and Minister of Finance Chrystia Freeland responds to a question during Question Period in the House of Commons Tuesday December 8, 2020 in Ottawa. The stage is set for arguably the most important federal budget in recent memory, as the Liberal government prepares to unveil its plan for Canada’s post-pandemic recovery even as a third wave of COVID-19 rages across the country. THE CANADIAN PRESS/Adrian Wyld
Election reticence expected to temper political battle over federal budget

Opposition parties have laid out their own demands in the weeks leading up to the budget

A syringe is loaded with COVID-19 vaccine at a vaccination clinic run by Vancouver Coastal Health, in Richmond, B.C., Saturday, April 10, 2021. THE CANADIAN PRESS/Jonathan Hayward
B.C. to open up COVID vaccine registration to all B.C. residents 18+ in April

Registration does not equate to being able to book an appointment

Pat Kauwell, a semi-retired construction manager, lives in his fifth-wheel trailer on Maxey Road because that’s what he can afford on his pension, but a Regional District of Nanaimo bylaw prohibits using RVs as permanent dwellings, leaving Kauwell and others like him with few affordable housing options. (Chris Bush/News Bulletin)
Rules against RV living hard on Island residents caught in housing crunch

Regional District of Nanaimo bylaw forcing pensioner to move RV he calls home off private farm land

(Black Press file photo).
UPDATED: Multiple stabbings at Vancouver Island bush party

Three youths hospitalized after an assault in Comox

Selina Robinson is shown in Coquitlam, B.C., on Friday November 17, 2017. British Columbia’s finance minister says her professional training as a family therapist helped her develop the New Democrat government’s first budget during the COVID-19 pandemic, which she will table Tuesday. THE CANADIAN PRESS/Darryl Dyck
B.C. finance minister to table historic pandemic-challenged deficit budget

Budget aims to take care of people during pandemic while preparing for post-COVID-19 recovery, Robinson said

Each spring, the Okanagan Fest-of-Ale is held in Penticton. This year, as a result of the COVID-19 pandemic, the festival will not be held. However, beer is still available. How much do you know about this beverage? (pxfuel.com)
QUIZ: How much do you really know about beer?

Put your knowledge to the test with this short quiz

Lord Tweedsmuir’s Tremmel States-Jones jumps a player and the goal line to score a touchdown against the Kelowna Owls in 2019. The face of high school football, along with a majority of other high school sports, could significantly change if a new governance proposal is passed at the B.C. School Sports AGM May 1. (Malin Jordan)
Power struggle: New governance model proposed for B.C. high school sports

Most commissions are against the new model, but B.C. School Sports (BCSS) and its board is in favour

Most Read