In this image made from video provided by Johns Hopkins Medicine, surgeons operate on Nina Martinez of Atlanta, who’s thought to be the world’s first kidney transplant living donor with HIV, in Baltimore on Monday, March 25, 2019. Doctors transplanted one of Martinez’s kidneys into an HIV-positive recipient who chose to remain anonymous. (Johns Hopkins Medicine via AP)

US begins organ transplants from living donors who have HIV

The move could free up space on the transplant list

Surgeons in Baltimore have performed what’s thought to be the world’s first kidney transplant from a living donor with HIV, a milestone for patients with the AIDS virus who need a new organ. If other donors with HIV come forward, it could free up space on the transplant waiting list for everyone.

Nina Martinez of Atlanta travelled to Johns Hopkins University to donate a kidney to an HIV-positive stranger, saying she “wanted to make a difference in somebody else’s life” and counter the stigma that too often still surrounds HIV infection.

Many people think “somebody with HIV is supposed to look sick,” Martinez, 35, told The Associated Press before Monday’s operation. “It’s a powerful statement to show somebody like myself who’s healthy enough to be a living organ donor.”

Hopkins, which is making the transplant public on Thursday, said both Martinez and the recipient of her kidney, who chose to remain anonymous, are recovering well.

“Here’s a disease that in the past was a death sentence and now has been so well controlled that it offers people with that disease an opportunity to save somebody else,” said Dr. Dorry Segev, a Hopkins surgeon who pushed for the HIV Organ Policy Equity, or HOPE, Act that lifted a 25-year U.S. ban on transplants between people with HIV.

There’s no count of how many HIV-positive patients are among the 113,000 people on the nation’s waiting list for an organ transplant. HIV-positive patients can receive transplants from HIV-negative donors just like anyone else.

Only in the last few years, spurred by some pioneering operations in South Africa, have doctors begun transplanting organs from deceased donors with HIV into patients who also have the virus, organs that once would have been thrown away.

Since 2016, 116 such kidney and liver transplants have been performed in the U.S. as part of a research study, according to the United Network for Organ Sharing, or UNOS, which oversees the transplant system. One question is whether receiving an organ from someone with a different strain of HIV than their own poses any risks, but so far there have been no safety problems, said UNOS chief medical officer Dr. David Klassen.

Hopkins’ Segev said Monday’s kidney transplant was a world first. Doctors had hesitated to allow people still living with HIV to donate because of concern that their remaining kidney would be at risk of damage from the virus or older medications used to treat it.

But newer anti-HIV medications are safer and more effective, Segev said. His team recently studied the kidney health of 40,000 HIV-positive people and concluded that those with well-controlled HIV and no other kidney-harming ailments like high blood pressure should face the same risks from living donation as someone without HIV.

“There are potentially tens of thousands of people living with HIV right now who could be living kidney donors,” said Segev, who has advised some other hospitals considering the approach.

Generally, kidneys from living donors last longer, added Dr. Niraj Desai, the Hopkins surgeon caring for the recipient. And if more people living with HIV wind up donating, it helps more than HIV-positive patients who need a kidney.

“That’s one less person waiting for a limited resource,” Desai said. “That helps everybody on the list.”

READ MORE: B.C. opioid crisis to get same world-renowned treatment approach as HIV

READ MORE: Second man seems to be free of AIDS virus after transplant

Martinez, a public health consultant, became interested in living donation even before HIV-to-HIV transplants began. Then last summer she learned that an HIV-positive friend needed a transplant, and tracked down Segev to ask if she could donate.

Her friend died before Martinez finished the required health tests but she decided to honour him by donating to someone she didn’t know.

A runner who plans on making this fall’s Marine Corps Marathon, “I knew I was probably just as healthy as someone not living with HIV who was being evaluated as a kidney donor,” Martinez said. “I’ve never been surer of anything.”

___

Lauran Neergaard, The Associated Press


Like us on Facebook and follow us on Twitter.

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Saanich dog walkers react to potential review of bylaws allowing off-leash dogs on beaches

Focus should have remained on migratory birds, not on dog behaviour, says Cadboro Bay dog walker

UPDATED: Demonstrators plan to shut down Pat Bay Highway Wednesday afternoon

Adam Olsen, MLA, says issue should be taken to province, not communities

North Saanich’s Deep Cove Market up for sale for almost $1.8 million

Long-time owner Rosemary Scott hopes the public will understand her decision

Council approve temporary storage to extend life of Oak Bay Fire Hall

It’s cute, it’s iconic, but the picturesque Oak Bay Fire Hall is… Continue reading

No dogs allowed off-leash at Luxton Fairgrounds in Langford

New sign placed by Metchosin Farmers Institute on Wednesday, Feb. 19

Protecting privacy key to stopping spread of COVID-19, B.C. health officials say

The number of coronavirus cases in B.C. remains at seven

Toffoli scores OT winner as Canucks beat Habs 4-3

Demko makes 37 saves for Vancouver

Private clinics would harm ‘ordinary’ people using public system in B.C.: lawyer

Health Minister Adrian Dix announced in 2018 that the government would begin to fine doctors $10,000

B.C. terminates contract with hospice society refusing assisted death

Delta Hospice Society loses hospital service fund of $1.5 million

Child in hospital following fatal crash that killed father, sibling on B.C. highway

The single vehicle crash occured near Kamloops on Highway 5A

‘Die!’: Vernon councillor mailed death threat

This story contains information that might be sensitive to some readers

Hidden message connects Castlegar homeowners decades apart

The Rodgers family was surprised when a message fell out of the walls as they were renovating

Two B.C. men plead guilty to bus-terminal assault of man with autism in Ontario

Parmvir Chahil and Jaspaul Uppal due to be sentenced in June for aggravated assault

Most Read